Oleoylethanolamide (OEA) 85% 98% 111-58-0 CHINA supplier best price CAS NO.111-58-0

Product introduction

Bioactive lipid amide OEA is synthesized in the gastrointestinal tract and is related to several unique steady-state properties, including anti-inflammatory activity, immune response, stimulation of fat decomposition and fatty acid oxidation. OEA is derived from omega-9 monounsaturated fatty acid oleic acid. It is considered to be an endogenous cannabinoid like lipid, and it is a receptor activated by peroxisome proliferators α （PPAR- α） Interacting and mediating anti-inflammatory processes. In addition, fatty acid ethanolamide is a lipid mediator that regulates a large number of physiological functions. Oleoyl ethanolamide (OEA), as such a biologically active lipid medium, is a peroxisome proliferator activated receptor- α （PPAR- α） An effective agonist that regulates the increased expression of fatty acid transferase CD36, thereby regulating eating behavior. In addition, OEA is an endogenous fatty acid ethanolamine produced in the intestinal mucosa. OEA anorexia signal may be the basic element of the physiological and metabolic system regulating dietary fats intake and obesity. The intake of oleic acid and the resulting OEA that endows anorexia characteristics depend on CD36, PPAR- α， Intestinal adipose sensory receptors, histamine, oxytocin, and dopamine; Causing an increase in fat oxidation and energy expenditure to induce satiety and increase feeding latency; And any interruption in these systems will stop or suppress the feeling of fullness caused by fat.

Application areas

Oleoyl ethanolamide is a natural ethanolamide lipid that can be used as a dietary program and weight regulator for various vertebrates. It is a metabolite of oleic acid formed in the human small intestine. It adheres to the PPAR Alpha receptor and helps control four factors: hunger, body fat, cholesterol, and body weight. PPAR Alpha represents the receptor alpha activated by peroxide proliferators.

Product features

(1) Oleoyl ethanolamide (OEA) is a molecule produced in the body and typically present in the intestine.

(2) Oleoyl ethanolamide (OEA) is a molecule that regulates lipid metabolism and energy homeostasis. Therefore, OEA may have beneficial metabolic effects on NAFLD patients.

(3)Bioactive lipid amide oleoyl ethanolamide (OEA) has several unique steady-state properties, including anti-inflammatory activity, immune response regulation, and antioxidant effects.

About us

Myland is an innovative life sciences supplements, custom synthesis and manufacturing services company. We are FDA registered manufacturer securing human health with consistent quality, sustainable growth. We manufacture and source a vast range of nutrition supplements pharmaceutical products and take pride in delivering them while others cannot. We are experts in both small molecules and biological raw materials. We provide a full range of products and services to support life science research and development, with around a hundred complex manufacturing service projects. 

Our R&D resources and production facilities, analytical instruments are modern and versatile, allowing us to produce chemicals on the milligram-to-ton scale, and at ISO 9001 and GMP.

With chemistry & biology specialties and manufacturing services from the first idea to the finished product, from route scouting to GMP or ton-scale production. We keep central warehouse in Suzhou SIP to ensure a strict QC process is carried out with only high-quality products can be released.  In the meantime, we set up sub-warehouses in both the USA and Europe to ensure the products reach our customers as quickly as possible.