Manufacturer Supplies High-quality 5-Amino-1-methylquinolinium chloride CAS No.:42464-96-0 98.0% purity min. CAS NO.42464-96-0

1.Product introduction

5-Amino-1-methylquinolinium chloride is an enzyme overexpressed during skeletal muscle aging and is associated with repair of NAD+ pathway damage, dysregulated sirtuin1 activity, and increased muscle stem cell senescence. 5-Amino-1-methylquinolinium chloride promotes myoblast differentiation in vitro and enhances fusion and regeneration of muscle stem cells in aged mice. 5-Amino-1-methylquinolinium chloride is also a potent inhibitor of nicotinamide N-methyltransferase (NNMT), selectively binding to NNMT substrate binding site residues. 5-Amino-1-methylquinolinium chloride promotes myoblast differentiation in vitro and enhances fusion and regeneration of muscle stem cells in aged mice. Among them, the cytosolic enzyme nicotinamide N-methyltransferase (NNMT) has been newly discovered to regulate the levels of nicotinamide precursors required for NAD+ biosynthesis, and therefore plays a crucial role in regulating the NAD+ salvage pathway and cellular metabolism.

5-Amino-1-Methylquinolinium Chloride works within your microbiome to reduce adipose (fat) tissue and help you lose weight.When extra fat cells accumulate, your body overproduces an enzyme known as NNMT (nicotinamide N-methyltransferase). The more NNMT, the more your body increases inflammation and stores fat. 5-Amino-1-Methylquinolinium Chloride inhibits NNMT, allowing your body to drop excess weight.

Feature

(1) High purity: 5-Amino-1-methylquinolinium chloride can obtain high-purity products through refined production processes. High purity means better bioavailability.

(2) Targeting: 5-Amino-1-methylquinolinium chloride specifically targets the NNMT enzyme and can effectively inhibit its activity, thereby affecting the metabolic pathway of nicotinamide.

(3) Stability: 5-Amino-1-methylquinolinium chloride has good stability and can maintain its activity and effect under different environments and storage conditions.

(4) Development prospects: Due to the various characteristics of NNMT, its development has received widespread attention and has broad research and application prospects.

Applications

5-Amino-1-methylquinolinium chloride is a nicotinamide N-methyltransferase (NNMT) inhibitor that promotes myoblast differentiation. 5-Amino-1-methylquinolinium chloride can also be used as a supplement to help reduce weight and fat and improve liver fat.

 【Frequently Asked Questions】
 【1】Q: What is your delivery time?
           A: Generally 1~5 days after receiving payment.
 【2】Q: Where is your shipping port?
            A: Shanghai/Ningbo.
 【3】Q: What is the specific form of packaging?
            A: Usually our packaging is 1kg/bag and 25kg/barrel. Of course, if you have special requirements, we will also package them according to your requirements.
 【4】Q: Can your company accept customization and meet customers' specific specifications?
            A: Yes, we can.
 【5】Q: Can your company provide samples?
             A: Yes, we can, please contact us by phone for specific sample information.